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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMS1
All Species:
10.61
Human Site:
T465
Identified Species:
21.21
UniProt:
P54277
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54277
NP_000525.1
932
105830
T465
F
I
S
S
V
K
H
T
Q
S
E
N
G
N
K
Chimpanzee
Pan troglodytes
XP_515987
1061
120272
T594
F
I
S
S
V
K
H
T
Q
S
E
N
G
N
K
Rhesus Macaque
Macaca mulatta
XP_001103074
831
93641
H420
A
G
D
F
G
Y
G
H
C
S
S
E
I
S
N
Dog
Lupus familis
XP_536002
930
105612
T465
F
V
V
S
V
K
H
T
Q
S
E
N
G
N
K
Cat
Felis silvestris
Mouse
Mus musculus
P54279
859
95207
T444
G
P
E
T
A
E
L
T
R
S
F
P
S
E
K
Rat
Rattus norvegicus
NP_001009535
919
103710
G465
Q
G
E
N
G
R
S
G
T
G
E
N
G
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507554
871
92244
A456
G
S
A
L
P
D
D
A
P
P
S
G
T
P
L
Chicken
Gallus gallus
NP_001006508
916
103017
K461
A
P
V
D
P
G
S
K
E
E
G
G
C
L
L
Frog
Xenopus laevis
NP_001079545
925
103654
I465
D
T
E
S
L
N
P
I
D
S
V
H
Q
V
S
Zebra Danio
Brachydanio rerio
NP_958476
896
98728
A456
G
P
E
S
Q
I
S
A
E
N
W
S
A
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188203
734
80915
A323
S
G
A
S
A
Q
T
A
T
G
A
T
C
D
V
Poplar Tree
Populus trichocarpa
XP_002321013
915
101109
E467
Q
C
P
S
R
V
V
E
R
V
K
G
D
S
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.4
86.2
83.6
N.A.
22.3
73.7
N.A.
35.9
58.3
50.7
46.1
N.A.
N.A.
N.A.
N.A.
28.3
Protein Similarity:
100
87.7
87.7
92.6
N.A.
41.6
86
N.A.
50.7
74.6
69
64.6
N.A.
N.A.
N.A.
N.A.
45.8
P-Site Identity:
100
100
6.6
86.6
N.A.
20
20
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
40
33.3
N.A.
6.6
6.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
17
0
17
0
0
25
0
0
9
0
9
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
9
0
0
0
17
0
0
% C
% Asp:
9
0
9
9
0
9
9
0
9
0
0
0
9
9
9
% D
% Glu:
0
0
34
0
0
9
0
9
17
9
34
9
0
17
0
% E
% Phe:
25
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
25
25
0
0
17
9
9
9
0
17
9
25
34
9
0
% G
% His:
0
0
0
0
0
0
25
9
0
0
0
9
0
0
0
% H
% Ile:
0
17
0
0
0
9
0
9
0
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
25
0
9
0
0
9
0
0
0
34
% K
% Leu:
0
0
0
9
9
0
9
0
0
0
0
0
0
9
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
9
0
34
0
25
17
% N
% Pro:
0
25
9
0
17
0
9
0
9
9
0
9
0
9
0
% P
% Gln:
17
0
0
0
9
9
0
0
25
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
9
9
0
0
17
0
0
0
0
0
9
% R
% Ser:
9
9
17
59
0
0
25
0
0
50
17
9
9
17
9
% S
% Thr:
0
9
0
9
0
0
9
34
17
0
0
9
9
0
0
% T
% Val:
0
9
17
0
25
9
9
0
0
9
9
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _